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ATS Assembly on Respiratory Structure & Function Project Proposal Initiative

The American Thoracic Society provides financial support for Assembly Project Proposals. The Respiratory Structure & Function Assembly has created this short survey to assess the needs and interests of its members for projects such as workshops. This is your voice! Your responses will be used to launch initiatives for the development of working groups to “champion” priority Project Proposals. Projects are intended to highlight areas of significant importance and/or controversy, and foster interaction between ATS members and individuals of diverse expertise that may not routinely interact with ATS members. Projects typically lead to development of documents (eg. published reviews, proceedings, policy statements, or Guidelines & Recommendations) though other outcomes (eg. DVD) can also be developed.

Please take a moment to complete this survey – it will take only a few minutes. If you are interested in funding for a project or participating in a project please include your name below to be considered for a working group (leader or member).


PART 1: Hot Topics

Provide up to three suggestions for existing or new areas of significant importance or controversy that you feel should be considered for project development:

PART 2: Suggested Topics

Review the topics below (organized under the main research categories for RSF). Rate topics on a scale of 1-5 where 1 is the most desirable and 5 the least desirable.

Acute Lung Injury

Most Desirable Desirable Somewhat Desirable Not Desirable Least Desirable
Cytoskeletal dynamics in lung health and disease
Immune response in ventilator-injured lungs
Advances in ventilator technology and modalities
Osmotic stress and lung injury & repair

Lung (Patho)Physiology and Mechanics

Most Desirable Desirable Somewhat Desirable Not Desirable Least Desirable
Murine models of asthma– strengths, weaknesses, opportunities and threats
Neural control of the airways
Modulation of the cough reflex
TRP channels in airway pathobiology
Quantifying emphysema in humans and mice
Neuropeptide modulation airway mechanics in asthma
Influence of the epithelium on airway calibre
Small airway function: inflammation, airway calibre and heterogeneity
Airway hyperresponsiveness: molecules to man
Role of lung surfactant in modulating airway mechanics in asthma
Gender differences in health, aging and lung disease
Vascular barrier properties
Interstitial matrix molecules and tissue mechanics
Use of the forced oscillation technique
Severe asthma – causes, consequences and treatment
Pathobiology of rare lung diseases
Aging of the pulmonary system

Airway Smooth Muscle & Airway Remodeling
Most Desirable Desirable Somewhat Desirable Not Desirable Least Desirable
Developing in vivo methods for measuring airway remodeling
Epithelial-mesenchymal transition in airway and lung remodeling
Vascular remodeling in pulmonary hypertension, asthma and COPD
Airway smooth muscle remodeling and dysfunction in asthma and COPD
Targeting airway remodeling in asthma treatment
Apoptosis and fibrotic lung disease
Association between asthma phenotype and airway remodeling

Integrating Structure and Function: Imaging and Modeling

Most Desirable Desirable Somewhat Desirable Not Desirable Least Desirable
Lung imaging: integrating lung and cell mechanics
Mathematical modeling of lung disease
Imaging: novel techniques
Imaging: early detection of disease
Imaging: physiological mechanisms in health and disease
Ventilation heterogeneity: theoretical modeling to imaging
Nanotechnology in detecting and treating lung disease

Respiratory and Peripheral Muscle Biology/Physiology
Most Desirable Desirable Somewhat Desirable Not Desirable Least Desirable
Cell and molecular mechanisms for respiratory and peripheral muscle failure
Respiratory and peripheral muscle dysfunction in sepsis
Skeletal muscle weakness in COPD
Respiratory muscle failure in muscular dystrophy
Acquired weakness syndromes in critical illness
Mechanical ventilation induced diaphragm dysfunction
Mechanisms for exercise endurance in asthma and COPD
Exercise rehabilitation programs for COPD

Other:

Most Desirable Desirable Somewhat Desirable Not Desirable Least Desirable
Hypertonic saline inhalation for cystic fibrosis
Genetics of COPD

If you would like to be considered for inclusion in a Project Development working group please provide your contact information and identify the project(s) of interest to you below:








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