Psychotic and Mood Disorders Pretest

The editors of The Journal of Family Practice and Current Psychiatry would like insight into your current knowledge about diagnosing and managing psychotic and mood disorders. Please note that these questions will not affect your CME test score.

1) First-generation antipsychotics are often associated with which extrapyramidal symptoms?

Dizziness   Erectile dysfunction   Tardive dyskinesia   All of the above

2) What effect does cigarette smoking have on patients taking antipsychotics?

Smoking increases the metabolism of antipsychotics that act primarily via CYP1A2; therefore, it may be necessary to increase the dosage of those antipsychotics   Smoking does not alter the mechanism of action of antipsychotics   Smoking has a minimal effect on how antipsychotics work; therefore it is unnecessary to modify dosages

3) Of the following, which has been associated with the greatest weight gain?

Risperidone   Olanzapine   Quetiapine   Ziprasidone   Aripiprazole

4) What typically causes medication-related weight gain in patients taking antipsychotics?

Reduced physical activity due to somnolence   Medication impacts certain neural pathways that can alter the sensation of hunger and satiety   Many drugs used in combination with atypical antipsychotics are known to cause weight gain   All of the above

5) Reported nonadherence (including partial adherence) by patients with schizophrenia is as high as 80%. Which of the following are factors in the high rates of nonadherence for these patients?

Lack of insight into the illness   Substance abuse   Side effects and tolerability of agents   Cognitive deficits   All of the above